Researchers conducted a controlled study on trained male lifters who followed the same 8-week hypertrophy + strength training program.

Participants were randomly assigned to receive 750 mg of Mediator® Phosphatidic Acid per day or a visually identical placebo.

Before and after the study, scientists measured:

• Lean body mass (DEXA scans)
• Muscle thickness (ultrasound)
• Strength (1RM bench press & squat)
• Body fat changes
• Quad cross-sectional area

The goal was simple:
See whether adding PA to a structured training program could speed up strength and muscle growth — without changing anything else.

It did. Significantly.

Both groups trained hard.
Both groups followed the exact same program.
Both groups received the same post-workout protein.

The only difference was that one group took Phosphatidic Acid (Mediator®) and the other did not.

The results at the end of the study were clear:

• The PA7® group built roughly twice as much lean muscle
• The PA7® group gained significantly more strength
• The PA7® group lost more fat
• The placebo group showed only standard training-driven progress
  

The takeaway:
When everything else is equal, PA7® unlocks additional muscle-building potential that training alone cannot.

Every rep you perform sends a mechanical signal to your muscles.
PA7® strengthens that signal.

Here’s the simplified pathway:

1. Resistance training triggers the muscle-building response. Your body naturally starts the process of muscle protein synthesis after you lift.
   
   
2. Phosphatidic Acid (PA) amplifies that response. PA interacts with key cellular proteins that control how quickly and efficiently your body starts rebuilding damaged muscle fibers.
   
   
3. A stronger signal = more protein synthesis. This means more rebuilding, more repairing, and more muscle growth from the exact same workouts you’re already doing.
   
   
4. Natural, safe, and non-hormonal. Unlike steroids or hormonal agents, PA works with your body’s existing pathways. No hormones altered. No artificial stimulation. No side effects associated with hormone-based muscle builders.
   

Think of training as the spark — and PA7® as the amplifier that ensures your body makes the most of every rep.

Muscle growth is a progressive, adaptive process.
The clinical trials found:

• Weeks 1–3: Improved recovery, better pumps, stronger mind–muscle connection
  
• Weeks 4–8: Noticeable increases in strength and training volume
  
• Weeks 8–12: Peak results in muscle thickness, lean body mass, and fat loss
  

As your body repeatedly triggers muscle protein synthesis through training, PA7® enhances that response — creating a cumulative effect that becomes most noticeable after 60+ days of consistent use.

This is why PA7® performs best when taken continuously for 8–12 weeks, just like it was used in the clinical trials.